The idea of pausing the aging process sounds like science fiction, but for some remarkable creatures, it’s a natural part of their survival strategy. You clicked to learn about animals that can naturally pause aging, and the reality is even more fascinating than you might imagine. Let’s explore the incredible organisms that have mastered the art of stopping time.
When we talk about “pausing aging,” we aren’t referring to a long lifespan, like that of a Greenland shark or a giant tortoise. Instead, we’re talking about a biological state called cryptobiosis, or suspended animation. During this state, an organism’s metabolic processes come to a near-complete standstill. They are not growing, developing, or aging. They are essentially in a state of reversible death, waiting for conditions to become favorable again. Several animals have perfected this incredible ability.
Perhaps the most famous masters of suspended animation are tardigrades, also known as water bears or moss piglets. These microscopic, eight-legged invertebrates are virtually indestructible. Their secret lies in their ability to enter a state of cryptobiosis called anhydrobiosis when faced with dehydration.
To survive, a tardigrade curls into a desiccated ball called a “tun.” In this state, it replaces the water in its cells with special sugars and proteins that form a protective, glass-like substance. This process, called vitrification, prevents its cellular structures from being destroyed.
Many people know brine shrimp by their popular brand name, “Sea-Monkeys.” These tiny crustaceans have a remarkable survival trick that allows their species to endure long periods of drought. They can produce embryos, called cysts, that enter a state of suspended animation.
These cysts are incredibly resilient. They can remain dormant for many years, completely dry and seemingly lifeless. During this time, all metabolic activity is paused, and the aging process is completely halted. The embryos inside are simply waiting. When the cysts are returned to saltwater, the conditions trigger the developmental process to resume, and they hatch into baby brine shrimp as if no time has passed at all.
The African turquoise killifish lives a fast and short life, typically lasting only a few months. This is because its home is in temporary pools of water that form during the rainy season in parts of Africa. When the pools dry up, the adult fish perish. So how does the species survive?
The answer is an embryonic state of suspended animation called diapause. The fish lay their eggs in the mud before the pool dries out. These embryos can enter a dormant state, pausing their development for months or even years. They are protected by a hardy outer shell and simply wait for the next rains to arrive. When the pools refill, their development restarts, they hatch, and a new generation is born. This ability to pause the “clock” before life truly begins is a critical survival strategy.
While tardigrades and brine shrimp pause aging, one creature takes it a step further. The Turritopsis dohrnii, often called the immortal jellyfish, can theoretically live forever by reversing its aging process.
This tiny jellyfish, no bigger than a pinky nail, has a unique ability called transdifferentiation. Normally, a jellyfish goes through a life cycle from a stationary polyp on the seafloor to a free-swimming medusa (the classic jellyfish shape). For most jellyfish, this is a one-way street ending in death.
However, when the immortal jellyfish is stressed by injury, starvation, or old age, it can do something amazing. It can revert its cells back to their earliest form, transforming back into a polyp. From this new polyp, it can bud and grow into a new medusa, effectively resetting its life cycle. It’s not just pausing aging; it’s actively turning back the clock to start over. This process could repeat indefinitely, making it biologically immortal.
What’s the difference between a long lifespan and pausing aging? A long lifespan, like that of a 200-year-old tortoise, means the animal simply ages very slowly. It is still aging continuously. Pausing aging, as seen in tardigrades, means metabolic processes and development completely stop for a period before resuming. Biological immortality, seen in the immortal jellyfish, is the ability to revert to a younger state and bypass death from old age entirely.
Can humans learn from these animals to pause aging? Scientists are actively studying the genes and proteins that allow these animals to perform such incredible feats. For example, the mechanisms that protect tardigrade cells from damage during dehydration are of great interest for medicine, such as preserving organs for transplant or creating more stable vaccines. However, human biology is vastly more complex, and applying these principles to pause or reverse human aging is still firmly in the realm of future science.